Patient engagement is becoming an increasingly important layer of digital healthcare. The U.S. records around 1.0 billion physician-office visits each year, yet patients may forget 40–80% of medical information shortly after a clinical encounter. That gap creates room for products that turn complex medical information into clearer, more personalized guidance before and after care.
Patient engagement solutions span education, treatment adherence, care navigation, scheduling, monitoring and communication. The U.S. market is projected to reach $22.4 billion by 2030, reflecting growing demand from providers and life-science companies for tools that keep patients informed and engaged beyond the clinical encounter.
As healthcare records have become increasingly digitized, a new generation of startups is building on top of that infrastructure using AI, video, mobile workflows and connected data. The opportunity is moving beyond simply giving patients access to information: helping them understand what it means, what to do next and how to stay engaged between visits.
Firefly Bio
Acquired by Johnson & Johnson for $1B.
Developed cancer medicines that used antibodies to carry protein-degrading drugs directly into tumor cells.
Acquisition · Biotech · United StatesFounded 2022 · Exit 2026 · ~4 years to exit
Carmot Therapeutics
Acquired by Roche for up to $3.1B.
Developed injectable medicines targeting metabolic diseases, including obesity and diabetes.
Acquisition · Biotech · United StatesFounded 2008 · Exit 2024 · ~16 years to exit
Oak Street Health
IPO at ~$5.01B valuation.
Later acquired by CVS Health for $10.6B.
Offered primary care for older adults, coordinating preventive, chronic, and social support services.
IPO + later acquisition · Healthcare services · United StatesFounded 2012 · Exit 2020 · ~8 years to exit