Last updated September 17, 2026

BlueRay Precision

Developing research reagents to detect and measure CAR-T cells

Protein DesignCell TherapyImmuno-oncology

CAR-T research depends on measuring engineered immune cells accurately, but laboratories can obtain different results from the same type of sample. Variation in detection reagents, instruments and analysis methods makes it harder to compare experiments, track cells over time and interpret results across research sites.

BlueRay Precision offers research reagents that identify CAR- using engineered proteins. Its and detection kits work with standard flow cytometers and are designed to reduce background staining and variation between reagent batches.

Key Investor Signals

Reagents used at DKFZ and university research labs

Scientists at , Heidelberg University Hospital and University Hospital Erlangen use BlueRay reagents in hematology and cell-therapy research workflows.

More than €1M awarded through EXIST Forschungstransfer

BlueRay’s project was selected for more than €1 million through , with Mohamed Awwad leading the funded project at Heidelberg University Hospital.

More than 2,000 CAR-T samples analysed in development

Analytical development spans different CAR designs, receptor densities and spacer formats. CD19 dilution experiments detected CAR-positive populations down to 0.06%.

Other Positive Signals

  • Offers in-stock CD19 and BCMA research detection reagents in 30-test kits with and formats.
  • Recognized as a Heidelberg University spin-off through its Created at Heidelberg University label.

Team

Mohamed Hemaid Sayed Awwad

Co-founder & Managing Director

  • Leads translational immunology research as a Group Leader and Senior Scientist at Heidelberg University Hospital.
  • Brings over a decade of research experience, including projects on T-cell dysfunction in cancer and standardized diagnostics.
  • Combines a PhD in Cancer Immunology with an MBA from Frankfurt School and lectures in Immuno-Oncology at Heidelberg.

Michael Hundemer

Co-founder

  • Has led Heidelberg University Hospital’s Cell Therapy Laboratory since 2006, bringing two decades of direct cell-therapy experience.
  • Heads clinical and hematological diagnostics laboratories at Heidelberg University Hospital.
  • Researches T-cell immunology and multiple myeloma, directly overlapping BlueRay’s CAR-T detection focus.

Product

BlueRay Precision’s platform uses ready-to-use reagents to identify CAR-expressing cells by flow cytometry. Engineered proteins bind the target receptor, while controlled fluorescent labeling is designed to improve staining consistency across reagent batches.

Recognition across CAR designs

CD19 and BCMA antigen-based reagents bind the matching CAR recognition domain. Antigen and spacer engineering support detection across different receptor architectures, rather than relying on a single hinge design.

Controlled staining chemistry

An engineered is designed to limit nonspecific staining. Site-specific labeling and controlled -to-protein ratios aim to reduce lot-dependent variation in the fluorescence signal.

Standard laboratory workflow

The staining protocol uses 3 microlitres of reagent per test with a 15-minute incubation, followed by washing and flow-cytometer analysis. Researchers can combine it with other cell-identification .

Market Overview

CAR-T treatment is expanding beyond specialist trials into routine care for blood cancers, while research is extending to autoimmune disease. Laboratories need to characterize engineered cells during development and follow them over time. Differences in staining and analysis complicate comparisons between research sites.

The buyers for standardized detection tools include academic laboratories, biotechnology companies and cell-therapy developers. Established flow cytometers allow new reagents to fit existing equipment, while consumables support repeat purchasing. Research-use suppliers must still demonstrate reproducibility and compete with established reagent vendors.

Annual CAR-T patient deployment
6,082

Patients receiving CAR-T therapy in 2024 across countries covered by the activity survey.

CAR-T share of engineered-cell pipeline
66%

Share of the global genetically modified cell-therapy pipeline using CAR-T in Q2 2026.

Quarterly CARVYKTI therapy sales
~$657M

Global net trade sales of the BCMA-targeted CAR-T therapy in Q2 2026.

Global flow cytometry spending
$5.1B

Estimated 2025 market across flow cytometry instruments, reagents and services.

Comparable Outcomes

Cytometry reagents

BioLegend

Acquired by PerkinElmer for ~$5.25B

BioLegend supplied life-science antibodies and reagents spanning cytometry, multiplex assays, and bioprocessing. PerkinElmer completed the acquisition in September 2021 for approximately $5.25 billion.

Cell-therapy reagents

PeproTech

Acquired by Thermo Fisher for ~$1.85B

PeproTech manufactured recombinant proteins, including cytokines and growth factors, for cell and development, manufacturing and broader research. completed the acquisition in December 2021 for approximately $1.85 billion.

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Sources

This profile was built from public company materials, ecosystem sources, market references, and professional profiles.

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