Last updated October 2, 2026

BASE4 Biosciences

Developing blood tests for organ aging and women’s reproductive health

Women's HealthPrecision MedicineBiomarkers

Ovarian aging and hormonal changes can affect fertility, bone health and cardiovascular risk. Individual changes are difficult to capture with a single age-based measure, creating demand for more informative assessments of reproductive biology and health over time.

BASE4 Biosciences is developing molecular blood tests to help women understand reproductive health and organ aging. Its sex-specific models aim to turn biological signals into personalized insights for fertility, and preventive-health discussions.

Key Investor Signals

Raised $1M in pre-seed financing for multi-omic testing

, , , and angel investors backed BASE4’s April 2026 pre-seed round to develop its blood-based, sex-specific biological modeling platform.

Secured transferred IP for blood-based tissue modeling

BASE4 was established through a technology-transfer agreement, with the underlying patent transferred to the company for its blood-based biological-age analysis.

Built on sex-specific research across 44 human tissues

Scientific co-founders Soria and Martínez-Pérez co-authored the 2020 study mapping sex differences in across 44 human tissue sources.

Team

Pol Cervera

CEO and Co-founder

  • Co-founded Exheus, later , and led operations and digital product work on its blood-based RNA analysis platform.
  • Worked on business development and product operations for , a nutrition agent for patients with cardiometabolic conditions.
  • Has taught and mentored entrepreneurship at since 2023, covering product validation and startup operations.

José Manuel Soria

CSO and Co-founder

  • Has directed Sant Pau’s Genomics of Complex Diseases unit since 2006, leading research in personalized medicine and disease risk.
  • Co-founded Exheus and served as CSO from 2020 to 2024, translating blood-based gene-expression research into a health-testing business.
  • Completed postdoctoral research in haemostasis and thrombosis at from 1995 to 1998.

Ángel Martínez-Pérez

CTO and Co-founder

  • Has worked as a senior bioinformatics scientist at Sant Pau since 2007, building computational expertise in human genetic data.
  • Co-authored the 2020 Science study mapping sex differences in gene expression across 44 human tissue sources.
  • Co-developed , published in 2018, an R software package for genetic studies that model related individuals.

Product

BASE4 Biosciences analyzes blood-based gene activity and other molecular signals with models tailored by sex. It translates these measurements into tissue-level biological-age estimates and pathway insights for informational reproductive-health and preventive-health assessment.

Molecular blood analysis

A peripheral blood sample is processed to measure gene activity alongside other molecular signals. The platform combines transcriptomic and genetic information to characterize biological changes.

Sex-specific tissue models

AI models infer the functional state and of multiple tissues using sex-specific patterns. The approach is designed to capture biological differences relevant to ovarian and broader organ health.

Organ and pathway interpretation

Results link organ-level signals with molecular pathways that may explain altered tissue function. Reproductive-health insights are informational and are intended for discussion with a qualified healthcare professional.

Market Overview

Women’s health testing serves patients and clinicians assessing reproductive function, hormonal changes and longer-term health. Fertility assessment and menopause-related care create recurring demand for interpretable biological information, alongside established laboratory and imaging services.

The market spans clinical laboratories, specialist practices and consumer testing services. Blood-based and home-sampling formats broaden access to reproductive-health information, while digital interpretation supports follow-up discussions. Molecular profiling also serves research buyers studying treatment response.

Women’s health diagnostics market
$23.7B

Global women’s health diagnostics revenue is estimated at $23.7B in 2026.

Fertility-testing devices market
$2.5B

Global fertility-testing devices generated an estimated $2.5B in revenue in 2025.

Home use in fertility testing
44.38%

Home-care settings represented 44.38% of global fertility-testing device revenue in 2025.

Lifetime experience of infertility
1 in 6

WHO’s 2025 fact sheet says 1 in 6 people of reproductive age experience infertility in their lifetime.

Comparable Outcomes

Reproductive health testing

Modern Fertility

Acquired by Ro for more than $225M.

Offered at-home hormone tests that helped women understand fertility, , and reproductive planning. acquired in May 2021 for a reported value of more than $225M, expanding its reproductive-health testing offering.

Gene-expression testing

Genomic Health

IPO at ~$292M valuation. Later acquired by Exact Sciences for $2.8B.

Developed gene expression tests that predicted cancer recurrence and guided chemotherapy decisions. Exact Sciences announced its $2.8B acquisition of in July 2019 and completed the transaction in November 2019.

Interested in More Startups Like BASE4 Biosciences?

Get a curated pipeline of healthcare and life sciences startups aligned with your investment thesis.

Get Deal Flow

Sources

This profile was built from public company materials, ecosystem sources, market references, and professional profiles.

Get the DealBio Pulse

Weekly insights on health and longevity startups, standout founders, key markets, and notable exits.

You can unsubscribe at any time.