Adding fluid flow to cell culture plates for preclinical drug testing
Static cell cultures poorly reflect the fluid movement cells experience in the body, limiting their predictive value. More realistic flow systems often require bulky pumps and tubing, making them difficult to automate and integrate into routine pharmaceutical laboratory workflows.
ARTIC Technologies develops MACplate, a cell culture plate that uses magnetically driven microscopic hairs to circulate fluid. It works with standard Transwell supports and laboratory automation, with pilot applications in gut permeability and immuno-oncology.
What stands out about ARTIC Technologies
MACplate units are in pilot labs for gut permeability and immuno-oncology, with results informing the next hardware revision.
An exclusive TU/e licence covers the original magnetic actuation patent and related artificial-cilia fluid-control know-how.
Early MACplate experiments with Erasmus MC kidney organoids showed promising indications of improved viability and differentiation.
A TOMAC pilot at ibidi confirmed physiological flow generation, while identifying setup and integration usability challenges.
ARTIC was established as a spin-off of Eindhoven University of Technology following the TOMAC technology-development project.
Co-founder Hossein Amirabadi has over 13 years of microphysiological-systems R&D experience relevant to ARTIC’s cell-culture platform.
Before co-founding ARTIC in 2024, Hossein Amirabadi co-founded AZAR Innovations in 2021 to support organ-on-chip adoption.
The TU/e TOMAC project that led to ARTIC received a €150,000 ERC grant to develop magnetic-cilia flow for organ-on-chip systems.
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